Anaphylaxis

/ˌænəfɪˈlæksɪs/ noun

noun ·Rare ·Advanced level

Meaning at a glance

  • Primary sense: Extreme sensitivity to a substance such as a foreign protein or drug.
  • Grammar: anaphylaxis is listed as noun.
  • Nearest alternatives: allergy, considerateness, delicacy, empathy.
  • Usage evidence: Anaphylaxis is a serious and life-threatening allergic reaction.

How to use "anaphylaxis"

  1. Start with the primary definition, then check the part of speech before placing the word in a sentence.
  2. Compare nearby synonyms to make sure "anaphylaxis" carries the exact meaning, tone, and strength you need.
  3. Use the example sentence as a context check. If your sentence uses the word differently, confirm that the grammar still fits.

Meaning check

  • Does the word fit the sentence's grammar?
  • Does it match the intended tone rather than only the dictionary definition?
  • Would a simpler synonym be clearer for the reader?
  • Is there enough surrounding context to prevent ambiguity?

Source and review context

This entry combines structured lexical data with WordToolSet review checks. Definitions, examples, synonyms, and usage notes may come from different source tables, so the page is designed to show evidence from more than one angle before you rely on "anaphylaxis" in a final draft.

If a word has several senses, prefer the sense that matches your sentence's grammar and surrounding context. A correct definition can still be the wrong choice when the sentence needs a different register, emphasis, or level of specificity.

Before you rely on this definition

Read the first definition as a starting point, then check the example, synonyms, and part of speech before treating "anaphylaxis" as the right word for your sentence.

If your draft is formal, technical, persuasive, or sensitive, compare "anaphylaxis" with a nearby alternative so the final choice matches both meaning and reader expectation.

Compare nearby meanings

  • Use synonyms when you need a softer, stronger, simpler, or more specific word.
  • Use antonyms to check the boundary of the meaning and avoid accidental contrast.
  • Use the example sentence to confirm the word behaves naturally in context.
  • Keep the original wording when a replacement adds complexity without improving precision.

Definition decision workflow

1. Identify the role

Check whether "anaphylaxis" is acting as noun in your sentence. A definition is only useful when the grammar matches the way the word is being used.

2. Test the nearest option

Compare it with "allergy" and other nearby choices to see whether the sentence needs a softer, stronger, or more familiar word.

3. Confirm with context

Use the example sentence below as an evidence check, then read your own sentence out loud to catch tone or rhythm problems.

Review note: Definition pages are checked for source coverage, sentence evidence, synonym support, and editorial insight before they are treated as approval-ready pages. If the evidence is too thin, the page remains available to users but is kept out of the approval-facing indexed inventory.

Final meaning check

Before publishing a sentence with "anaphylaxis", ask whether the word helps the reader understand the idea faster. A precise word should reduce confusion, not simply make the sentence look more polished.

When the definition, synonym evidence, and example context point in the same direction, the word is usually a safer choice. When they conflict, revise the sentence or choose a clearer alternative.

Definitions

Noun
  1. 1
    Extreme sensitivity to a substance such as a foreign protein or drug. countable, uncountable
  2. 2
    hypersensitivity reaction to the ingestion or injection of a substance (a protein or drug) resulting from prior contact with a substance wordnet
  3. 3
    A severe and rapid systemic allergic reaction to an allergen, causing a constriction of the trachea, preventing breathing; anaphylactic shock. countable, uncountable

    "“Anyone who has experienced or witnessed an anaphylaxis reaction knows it can be very stressful deciding when to inject epinephrine to themselves or a child and often delay,” Dr. Jonathan Spergel, chief of the allergy program at Children’s Hospital of Philadelphia, said in a news release from ARS Pharmaceuticals."

Example

"Anaphylaxis is a serious and life-threatening allergic reaction."

Common questions

What does "anaphylaxis" mean?

Extreme sensitivity to a substance such as a foreign protein or drug.

What is a synonym for "anaphylaxis"?

Common synonyms include: allergy, considerateness, delicacy, empathy, exquisiteness, fineness.

How do you use "anaphylaxis" in a sentence?

Anaphylaxis is a serious and life-threatening allergic reaction.

How do you pronounce "anaphylaxis"?

Pronounced /ˌænəfɪˈlæksɪs/.

Etymology

Borrowed from French anaphylaxie, coined by French physiologist and parapsychologist Charles Richet and French zoologist Paul Portier from the Ancient Greek ᾰ̓νᾰ- (ănă-, “(intensifier) thoroughly”) from ᾰ̓νᾰ́ (ănắ, “to, again, upon”) and φύλαξις (phúlaxis, “protection, watching, guarding”).

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