B-52

noun, slang

noun, slang ·Uncommon ·College level

Definitions

Noun
  1. 1
    A cocktail shooter consisting of three distinct layers of coffee liqueur, Baileys and Grand Marnier.
  2. 2
    A combination of diphenhydramine, 5 mg of haloperidol, and 2 mg of lorazepam, widely used for the sedation of acutely agitated patients. informal

Etymology

Named for Boeing's B-52 Stratofortress, a bomber aircraft used in the Vietnam War.

Data sourced from Wiktionary, WordNet, CMU, and other open linguistic databases. Updated March 2026.