Chaperome
noun ·Rare ·Advanced level
Definitions
- 1 All the proteins called chaperones that assist in the folding of misfolded proteins in an organism, and other functions.
"The availability of chaperones and cochaperones for folding of cargo will be sensitive to the globalcellular pool that we now define as the chaperome, a general term to define the unique steady-state composition of chaperones and their regulators in a given cell type. It is well established that the chaperome can be altered by multiple signaling pathways to accommodate cellular stress and misfolding load."
Example
More examples"The availability of chaperones and cochaperones for folding of cargo will be sensitive to the globalcellular pool that we now define as the chaperome, a general term to define the unique steady-state composition of chaperones and their regulators in a given cell type. It is well established that the chaperome can be altered by multiple signaling pathways to accommodate cellular stress and misfolding load."
Etymology
From chaperone + -ome (suffix indicating the complete whole of a class of substances for a species or an individual), coined by American biochemist Xiaodong Wang and his collaborators in a November 2006 article in Cell: see the quotation.
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Data sourced from Wiktionary, WordNet, CMU, and other open linguistic databases. Updated March 2026.