Holdase

noun

noun ·Rare ·Advanced level

Definitions

Noun
  1. 1
    A particular kind of molecular chaperone that assists the non-covalent folding of proteins in an ATP-dependent manner. Holdases bind to protein folding intermediates to prevent their aggregation but without directly refolding them.

    "As a part of that network, holdase chaperones are able to communicate with other chaperones in the network, to achieve refolding of misfolded clients."

Example

More examples

"As a part of that network, holdase chaperones are able to communicate with other chaperones in the network, to achieve refolding of misfolded clients."

Etymology

From hold + -ase?

Data sourced from Wiktionary, WordNet, CMU, and other open linguistic databases. Updated March 2026.