Hyperfractionation
noun ·Rare ·Advanced level
Definitions
- 1 An especially highly divided form of fractionation: the division of a total dose of radiation into many small fractions. uncountable
"Treatment with several doses per day offers the prospect of a significant therapeutic gain using readily available low LET beams. These regimens can be classified as either accelerated fractionation or hyperfractionation according to their rationales. With accelerated fractionation a conventional number of dose fractions is delivered in a significantly shortened overall treatment time in order to reduce the opportunity for tumor cell regeneration during treatment. With hyperfractionation, on the other hand, a large number of significantly reduced dose fractions is used to give a greater total dose in a conventional overall treatment time."
Example
More examples"Treatment with several doses per day offers the prospect of a significant therapeutic gain using readily available low LET beams. These regimens can be classified as either accelerated fractionation or hyperfractionation according to their rationales. With accelerated fractionation a conventional number of dose fractions is delivered in a significantly shortened overall treatment time in order to reduce the opportunity for tumor cell regeneration during treatment. With hyperfractionation, on the other hand, a large number of significantly reduced dose fractions is used to give a greater total dose in a conventional overall treatment time."
Etymology
International scientific vocabulary, from hyper- + fractionation = hyper- + fraction + -ation.
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Data sourced from Wiktionary, WordNet, CMU, and other open linguistic databases. Updated March 2026.