Kinoid
noun ·Rare ·Advanced level
Definitions
- 1 An immunogenic preparation containing a biologically inactivated cytokine, used experimentally as a form of vaccination to induce the production of antibodies against overproduced cytokines in several immune-related conditions (e.g. systemic lupus erythematosus, AIDS and Crohn's disease).
"For this purpose, IFN alpha was chemically converted into a biologically inactive, but still immunogenic product, which we termed “kinoid”, reminiscent of that of bacterial toxins which have been transformed into toxoids for vaccination. […] Active “kinoid” immunization should permit to counteract the overproduction of the corresponding cytokine when involved in pathogenesis."
Example
More examples"For this purpose, IFN alpha was chemically converted into a biologically inactive, but still immunogenic product, which we termed “kinoid”, reminiscent of that of bacterial toxins which have been transformed into toxoids for vaccination. […] Active “kinoid” immunization should permit to counteract the overproduction of the corresponding cytokine when involved in pathogenesis."
Etymology
From (cyto)kine + -oid, modelled on toxoid. Coined by Bernard Bizzini and A. Achour in 1995.
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Data sourced from Wiktionary, WordNet, CMU, and other open linguistic databases. Updated March 2026.