What does "macrodose" mean?

A relatively large dose of (something, such as a drug or radiation), particularly as contrasted with a microdose.

How do you pronounce "macrodose"?

Pronounced //ˈmækɹoʊˌdoʊs//.

//ˈmækɹoʊˌdoʊs// noun, verb

noun, verb ·Rare ·Advanced level

Noun

1
A relatively large dose of (something, such as a drug or radiation), particularly as contrasted with a microdose.
"Here macrodose is defined as the average dose for a large-size object such as a liver or a tumour."

Verb

1
To take a relatively large dose of (something, particularly a drug), particularly as contrasted with microdosing.
"Much less expensive than either is macrodosing with vitamins C, D, and E, which has been shown to be beneficial in slowing the progression of osteoarthritis of the knee."

"Here macrodose is defined as the average dose for a large-size object such as a liver or a tumour."

From macro- + dose; contrast microdose.

Data sourced from Wiktionary, WordNet, CMU, and other open linguistic databases. Updated March 2026.