Mesothelin
noun
noun ·Rare ·Advanced level
Definitions
Noun
- 1 A protein found in mesothelial cells and overexpressed in several human tumors. uncountable
"CAR T cells targeting vascular endothelial growth factor receptor 2 (VEGFR2), epidermal growth factor receptor variant III (EGFRvIII), and mesothelin are being tested in patients with glioblastoma, pancreatic, ovarian and mesothelioma cancers."
Example
More examples"He also learned people with pancreatic cancer have elevated levels of a protein called mesothelin in their bloodstream, and that early detection is key to increasing the chances of surviving pancreatic cancer."
Etymology
From mesothelial + -in.
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Data sourced from Wiktionary, WordNet, CMU, and other open linguistic databases. Updated March 2026.