Metyrapone

//mɪˈtɪ.ɹə.pəʊn// noun

noun ·Rare ·Advanced level

Definitions

Noun
  1. 1
    A compound that inhibits the enzyme 17β-hydroxylase and prevents synthesis of glucocorticoids and mineralocorticoids by the adrenal gland, used chiefly for assessment of feedback control of the hypothalamic–pituitary axis in adrenal disease, and sometimes in the treatment of Cushing's syndrome and resistant edema; 2-methyl-1,2-di-3-pyridyl-1-propanone, C₅H₄N·CO·C(CH₃)₂·C₅H₄N. uncountable

Etymology

From meth- + (dip)yr(idyl) + -a- + (pro)p(an)one.

Data sourced from Wiktionary, WordNet, CMU, and other open linguistic databases. Updated March 2026.