noun ·4 syllables ·Rare ·Advanced level

Definitions

Noun

1. 1
   A chronic systemic autoimmune disease characterized by hardening the skin or other organs through excessive deposits of collagen. countable, uncountable
2. 2
   an autoimmune disease that affects the blood vessels and connective tissue; fibrous connective tissue is deposited in the skin wordnet

Synonyms

All synonyms

dermatosclerosisgenus sclerodermasclerodermsclerodermsystemic sclerosissystemic sclerosis

Etymology

From New Latin sclēroderma, from Ancient Greek σκληρός (sklērós, “hard”) + δέρμα (dérma, “skin, hide”). By surface analysis, sclero- + -derma.

Data sourced from Wiktionary, WordNet, CMU, and other open linguistic databases. Updated March 2026.