Superbug

noun, slang

noun, slang ·Moderate ·College level

Definitions

Noun
  1. 1
    A strain of bacteria that is resistant to many antibiotics (e.g., MDR, XDR). informal

    "But now we’re seeing increasing numbers of superbugs that survive antibiotics. One of the best-known —[is] MRSA, a kind of staph infection [that]— kills about 18,000 Americans annually. That’s more than die of AIDS."

  2. 2
    a strain of pest accidentally imported into Florida from the Middle East then spread to California where it is a very serious pest feeding on almost all vegetable crops and poinsettias wordnet
  3. 3
    Any pathogen resistant to many, even all, of the biocides or other agents used to treat similar pathogens. informal
  4. 4
    a strain of bacteria that is resistant to all antibiotics wordnet
  5. 5
    An invasive insect, Bemisia tabaci, that is a major pest of vegetable crops, both directly and as a virus vector. US

Example

More examples

"Gilmore said scientists are studying the pathogen's genes to identify targets for the development of new weapons to fight the superbug."

Etymology

From super- + bug.

Data sourced from Wiktionary, WordNet, CMU, and other open linguistic databases. Updated March 2026.