Acellularize

US 6,448,076 B2 METHOD FOR CHEMICALLY ACELLULARIZING A BIOLOGICAL TISSUE SAMPLE Robert G. Dennis, Ann Arbor, Mich.; William M. Kuzon, Jr., Dexter, Mich., and Paul S. Cederna, Ann Arbor, Mich., assignors [...] The Regents of the Method for chemically acellularizing a biological tissue sample.

Although many studies have been conducted and reported good results under these hypotheses, we wanted to improve the acellularizing processes, especially in the process of nuclease treating and the removal of phospholipids ...

Some groups have attempted to use animal tissues to produce suitable matrices (Steinhoff et al. 2000). Different technologies have been developed to acellularize these tissues.