Autorepression

An incomplete PadR motif is located in the p/o of lmrR, this palindromic sequence is only weakly recognized by LmrR. A proposed mechanism for the binding of LmrR to the p/o regions and the regulation of lmrCD and lmrR is as followed: the binding of two LmrR dimers to PlmrCD, together with an extensive binding of PlmrR by multiple LmrR dimers, results in a repression of lmrCD and a strong autorepression of lmrR.