Bitchy-pants

Near-synonyms: bitcher, grumpy pants, grump

I should just trust him, shouldn't I? I mean—what does Alicia Bitchy-pants know about anything?

That's close to what I have to put up with, only I don't think Little Ms. Bitchypants is sleeping with anyone at the office. She sure acts like it, though.

"Yes, he knows Larry, but will you stop it already with your bitchy-pants, Dani? It's obvious from your crankiness that you need to get laid."