Irk

It was a pleasure to meet you Stella, I am so sorry for whatever I said to irk you the wrong way.

It irks me doing all this work and have someone wreck it.

Let no man pray to Māna-Yood-Sushāī, for who shall trouble Māna with mortal woes or irk him with the sorrows of all the houses of Earth?

The trade-off between computation cost and precision results in tuning parameters […] being exposed to the user, a major irk to practitioners of data science.