Kinomics

Chemogenomics attempts to combine genomic data, structural biological data, classical dendrograms, and selectivity data to explore, define, and classify the medicinally relevant kinase space. Exploitation of this information in the discovery of kinase inhibitors defines practical kinase chemogenomics (kinomics).

In this new field of kinomics, approaches like this which combine a simple methodology with high predictive power are very welcome to digest the steadily growing amount of selectivity data.

Kinomics can be used to understand both the mechanism of action and the specificity of potential drugs.