Knobbed

a knobbed chromosome

1774, Oliver Goldsmith, An History of the Earth, and Animated Nature, London: J. Nourse, Volume 4, Chapter 11, The Camelopard, pp. 299-300, No animal, either from its disposition, or its formation, seems less fitted for a state of natural hostility; its horns are blunt, and even knobbed at the ends; its teeth are made entirely for vegetable pasture […]

The chairs […] were railed with white bars across the back and knobbed with gold; neither the railings nor the knobs invited to ease.

For it's been a hard life, thought Mrs. Dempster. What hadn’t she given to it? Roses; figure; her feet too. (She drew the knobbed lumps beneath her skirt.)