Litholytic

Varuna is one of the best litholytic herbs and has been used throughout the ages for the treatment of urolithiasis and crystalluria.

In the clinical practice, citric acid therapy has some problems, including its taste, large volume to drink, need for hospitalisation, and unpredictable litholytic effect.

Chance of recurrence The follow-up of patients who have become stone-free after combined ESWL/ adjuvant litholytic therapy is still relatively short.

Retrograde irrigation of the renal pelvis with litholytic solutions (Instrumental kidney stone chemolysis).

The secondary metabolites secreted by microbial flora of caves may cause chemical reactions with the substrate, contamination of the substrate. by pigments and lithogenic processes, litholytic processes, as well as cavern enlargement or speleotherm deposition.

Treatment options for symptomatic cholelithiasis include surgery, dissolution with oral bile salt litholytics or contact solvents, and current fragmentation.

Accordingly, citric acid, a calcium chelator, was selected as a pancreatic litholytic, and a 50-mg pancreatic stone was dissolved in vitro after 25 days ina solution of 3.9 mM/L citric acid, corresponding to a concentration of 749 μg/mL in the pancreatic juice following injection of citric acid into the canine duodenum.

Phyllanthus niuri (chanca piedra) herb is a traditional litholytic; its Spanish common name translates as “stone breaker.”