Macrothrombus

Diffuse pulmonary macrothrombi (including any clot or thrombus in arteries with a lumen >1 mm) are found frequently, and are present in the early, intermediate, and late stage of ARDS, although in the late stage they are fewer.

Endogenous thrombin potential controls the capability of blood for intensive generation of fibrin microthrombi (irrelative of whether they will be condensed on macrothrombus or washed out downstream).