Mycobacteriocidal

As our AgNP suppression studies were done at 4-hr time points, these data strongly indicate that the observed AgNP-mediated suppression of M.tb-induced MDM responses resulted from interferences of AgNP with M.tb-induced host cell signaling pathways and not from direct mycobacteriocidal effects of the AgNP. AgNO 3 used as a positive control for M.tb killing (see Material and Methods ) completely abrogated M.tb growth.