Retrosynthesis

1983, Francis A. Carey, Richard J. Sundberg, Advanced Organic Chemistry: Reactions and synthesis, Plenum Press, page 578, The retrosyntheses shown in Scheme 11.11 correspond to the syntheses in Schemes 11.12 and 11.13.

The retrosyntheses shown in Scheme 2 lead directly to acetylene-type retrons (14)-(16) (path a) or implicate the use of Dewar o-xylylene (17) (path b) and the smaller retrons (18)-(20); the latter path was the route we elected to pursue (Scheme 3).

For example, the above mentioned retrosynthesis of nacre [132] is as much bio-inspired as is the crystallization in presence of hydrophilic polymers [44], although in the first case, the original biomineral structure is reproduced, whereas in the latter case, no biomineral is reproduced but complex crystal morphologies are obtained.