Set up shop

He set up shop in his garage every Saturday.

They set up shop as venture capitalists on Sand Hill Road.

Homer’s entrepreneurial spirit proves altogether overly infectious. Homer gives Barney a pep talk when he encounters him dressed up like a baby handing out fliers (Barney in humiliating costumes=always funny) and it isn’t long until Barney has purchased a truck of his own and set up shop as the Plow King.

[…] these companies could enjoy support required to set up shop for the long term.