Take to heart

He really took it to heart when I asked him to reconsider.

Of course, with her weak heart and dropsy one couldn't expect that she could get about with him, but he spent two hours every evening in her room. He might well do what he could, for she has been a rare good friend to him. But that's all over, too. He never goes near her. And she takes it to heart. She is brooding and sulky and drinking, Mr. Holmes—drinking like a fish.