Weigh on

She had got rid of two of the secrets which had weighed on her for a fortnight, and was certain of a willing listener in Jane, [...]

The Crimean war weighed on him like a nightmare.

Her shame weighed on her like a physical oppression: the roof and walls seemed to be closing in on her, and she was seized by the impulse to get away, under the open sky, where there would be room to breathe.

[H]er cat [...] has been missing for two days, she tells me, and his unexplained absence has been weighing on her mind.

Lance Fritz, the president and C.E.O. of Union Pacific Railroad, said pulling out of Nafta would harm trade, which would in turn weigh on his business.