Leudet and Perrin discovered submaxillary engorgement, so that we may suppose the possibility of that engorgement having existed at the commencement of the adenia, but to so small an extent as not to attract the notice of the patient.
Source: wiktionary
Adenia, or hyperplasia of lymphatic glands leading to the formation of tumours, may be divided into a leucæmic and a simple adenia, according as it is or is not accompanied by leucæmic changes in the blood, which in the latter case is either not altered at all, or shows oligo- and poikilocytosis. The two forms of adenia may perhaps pass one into the other, and they also correspond mutually in the fact that in both the process need not remain restricted to isolated lymphatic glands, but advances from one to the other, and that, moreover, analogous growths may also occur in the spleen, the lymphoid follicles and adenoid tissue of the digestive tract, and even in organs which normally contain no adenoid tissue.
Source: wiktionary