Unfortunately, the majority of non-antibiotic agents belonging to different therapeutic groups, such as antianaplastics, antiarrhythmics, antihypertensives, antidepressives, anticonvulsatives, spasmolytics, and anti-inflammatory drugs, show only marginal direct antibacterial activity (MIC ≥3000 mg/L) [30 ,31 ].
Source: wiktionary