Cantankerosity

Sir, the gentleman from South Carolina [Mr. Keitt] made a speech, and if I may be allowed to coin a word, I will say it had more cantankerosity in it than any speech I ever heard on this floor.

Source: wiktionary

“This is a case for phlebotomy.” / “I’ll phlebotomize you!” retorted Vie, irascibly. / “Worse and worse Strong indications of internal cantankerosity, requiring an immediate application of Croton oil and ipecacuanha, infused in an oyster stew, to be superseded by a nicotine fumigation.

Source: wiktionary

The French philosophers call this transcendental, but a simpler and more befitting name is that of cantankerosity. […] A curious case of peculiar cantankerosity is related by Nordenskold in the account of one of his wonderful voyages. […] To have the means of prosperous wholesome life in hand, and to prefer the favourite diet that would certainly kill, is surely an instance of moral cantankerosity as much as the man who, according to Mr. Samuel Weller’s legend, ate the three shillingsworth of muffins and blew his brains out. […] I humbly think that this is a case of mental cantankerosity.

Source: wiktionary

It is a sad and astounding fact to relate, but even in literary life we meet with instances of cantankerosity.

Source: wiktionary