Newer and Investigational Approaches to Antireflux Therapy Several new therapeutic approaches to antireflux treatment have been developed, including endotherapies that have been approved by the Food and Drug Administration, investigational endoscopic techniques to enhance the antireflux barrier, and investigational pharmacologic agents.
Source: wiktionary
Although endotherapy was primarily used for the treatment of upper GI and peptic ulcer bleeding, these modalities have also been applied to patients with lower GI bleeding.
Source: wiktionary
Furthermore, the available data regarding outcomes from minor papilla endotherapy are almost exclusively retrospective, involve small patient samples, varying definitions for pain outcomes, and have follow-up durations that are generally limited.
Source: wiktionary