All fears, griefs, suspicions, discontents, imbonities, insuavities are swallowed up, and drowned in this Euripus, this Irish Sea, this Ocean of misery, as so many small brooks; 'tis coagulum omnium ærumnarum: which Ammianus applyed to his distressed Palladius, I say of our Melancholy man, hee is the cream of humane adversity, the quintessence, and upshots; all other diseases whatsoever, are but flea-bitings to Melancholy in extent […]
Source: wiktionary