Most studies on these markers have demonstrated that MIA has better sensitivity and prognostic potential than S100. 30, 31 Moreover, most of these studies have measured S100 using immunoradiometric and immunoluminescent assays or polymerase chain reaction (PCR). 32 - 34 We know that the ELISA test is routinely used in most clinical laboratories throughout Brazil, as its application is very broad and ranges from oncology to mycology. 35, 36 However, PCR and the other aforementioned assays are more specialized and may not be present in all laboratories, while ELISA is.
Source: wiktionary