Victorian women who weren’t locked up for falling victim to lypemania (melancholy), monomania, homicidal monomania or “moral insanity” were at risk of neurasthenia, a “mirror image of rebellion” in which their “nervous depletion” was explained as the result of their “incursion into the masculine sphere of intellectual labor,” a strain that constitutions formed for tender sentiment couldn’t be expected to support.
Source: wiktionary