Wild-type and Il22 -/- mice were intradermally infected with 2 x10 6 L . major promastigote metacyclics and cells from 5 week old lesions were collected and analyzed by flow cytometry. (A) Representative dot plots and bar graphs depict frequencies and total cell numbers of CD4+, CD8+, CD11b+, and LY6G+ cells. (B-C) RNA was isolated from the lesions of wild-type mice infected with L . major to assess gene expression.
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