Our results suggest that excessive activation of PARP-1 leads to an intrinsic cell death program, which we designate as parthanatos to distinguish from necrosis and apoptosis.
Source: wiktionary
Parthanatos
Synonyms for "parthanatos"
Ranked by relevance and common usage.
Related word relations
OpenGloss and ConceptNet supply richer edges like generalizations, collocations, and derivations.
derived from
2 entrieshas context
1 entriesrelated to
2 entriesSample sentences
3 total sentences available.
Also, the lack of knowledge of mechanisms of calpain activation in parthanatos makes it difficult to identify calpain as PAR-dependent mediators of AIF release.
Source: wiktionary
The biochemical features of parthanatos are distinct from classically defined pathways of cell death, and include rapid PARP-1 activation, early PAR accumulation, mitochondrial depolarization, early nuclear AIF translocation, loss of cellular NAD and ATP, and late caspase activation.
Source: wiktionary
Keep exploring
Data sourced from Wiktionary, WordNet, CMU, and other open linguistic databases. Updated March 2026.