Interestingly, the p-chloro- and p-trifluoromethyl-phenyl monophenols 10 and 11 retained activity (EC 50 = 4.0 ± 1.4 μM and 12.4 ± 6.9 μM, respectively) with an excellent selectivity versus proliferating TG1 GSCs, suggesting that pharmacomodulation is possible at this position.
Source: wiktionary