It is sometimes assumed that the concepts of LUCA and progenote are the same by definition; more correctly, it is hypothesised that LUCA was a progenote.
Source: wiktionary
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It is sometimes assumed that the concepts of LUCA and progenote are the same by definition; more correctly, it is hypothesised that LUCA was a progenote.
Source: wiktionary
Inaccuracy of information transfer would manifest itself in two ways that strongly shape the nature of the progenote. It would severely limit the number of different genes the progenote could carry, and the generally lower biological specificity would then mean that overall, fine-tuned, feed-back mechanisms that make the cell today the smooth functioning whole that it is, would be missing.
Source: wiktionary
The progenote model sees organisms as genetically communal and the community as evolving as a whole, not the individual cell lines therein.
Source: wiktionary
As to the physical nature and organization of progenotes, Woese was carefully and purposely agnostic, but he entertained the possibility that progenotes were precellular entities lacking even a bounding membrane.
Source: wiktionary
Data sourced from Wiktionary, WordNet, CMU, and other open linguistic databases. Updated March 2026.