Additionally, redistribution of the globules of submembrane VE-cadherin was found, while little discontinuity of VE-cadherin was observed at 10 μg/mL. Additionally, most of the cells exhibited regular separations from each other, and cells exposed to TNF-α and IL-6 along with the HO-1 inhibitor SnPP exhibited strong distribution of VE-cadherin on the cell border, indicating reduced permeability.
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