Smoothened
noun, verb
noun, verb ·Rare ·Advanced level
Definitions
Noun
- 1 A transmembrane protein belonging to the group of G protein-coupled receptors that is a key component of the hedgehog signaling pathway. uncountable
Verb
- 1 simple past and past participle of smoothen form-of, participle, past
Adjective
- 1 made smooth by ironing wordnet
Etymology
Etymology 1
From smoothen + -ed.
Etymology 2
Ultimately the same as etymology 1. The gene encoding the protein was first identified in Drosophila melanogaster as a segment polarity gene and initially named smooth (smo) by Christiane Nüsslein-Volhard et al. in 1984. This was later revised to smoothened by Dan L. Lindsley and Georgianna G. Zimm in 1992, because the former name already described another locus.
More for "smoothened"
Data sourced from Wiktionary, WordNet, CMU, and other open linguistic databases. Updated March 2026.