Smoothened

noun, verb

Definitions

Adjective
  1. 1
    made smooth by ironing wordnet
Noun
  1. 1
    A transmembrane protein belonging to the group of G protein-coupled receptors that is a key component of the hedgehog signaling pathway. uncountable
Verb
  1. 1
    simple past and past participle of smoothen form-of, participle, past

Etymology

Etymology 1

From smoothen + -ed.

Etymology 2

Ultimately the same as etymology 1. The gene encoding the protein was first identified in Drosophila melanogaster as a segment polarity gene and initially named smooth (smo) by Christiane Nüsslein-Volhard et al. in 1984. This was later revised to smoothened by Dan L. Lindsley and Georgianna G. Zimm in 1992, because the former name already described another locus.

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