Smoothened
noun, verb
noun, verb ·Uncommon ·Advanced level
Definitions
Noun
- 1 A transmembrane protein belonging to the group of G protein-coupled receptors that is a key component of the hedgehog signaling pathway. uncountable
Verb
- 1 simple past and past participle of smoothen form-of, participle, past
Adjective
- 1 made smooth by ironing wordnet
Etymology
Etymology 1
From smoothen + -ed.
Etymology 2
Ultimately the same as etymology 1. The gene encoding the protein was first identified in Drosophila melanogaster as a segment polarity gene and initially named smooth (smo) by Christiane Nüsslein-Volhard et al. in 1984. This was later revised to smoothened by Dan L. Lindsley and Georgianna G. Zimm in 1992, because the former name already described another locus.