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Disquietude

//dɪˈskwaɪə.tud// noun

Noun

1
A state of disquiet, uneasiness, or anxiety. uncountable, usually
"One would think there should be something wonderfully pleasing in the Possession of Fame, that, notwithstanding all these mortifying Considerations, can engage a Man in so desperate a Pursuit; and yet if we consider the little Happiness that attends a great Character, and the Multitude of Disquietudes to which the Desire of it subjects an ambitious Mind, one would be still the more surprised to see so many restless Candidates for Glory."
2
feelings of anxiety that make you tense and irritable wordnet
3
A fear or an instance of uneasiness. countable, usually
"The cares and disquietudes of the marriage-state, quoth Mrs. Wadman, are very great."

From dis- + quietude.

Unscramble this word: disquietude