Endobiotic

adj, noun

adj, noun ·Rare ·Advanced level

Definitions

Noun
  1. 1
    An endogenous substance that influences the functioning of an organ or biological process.

    "ADME and chemical reactivity-related toxicity is low, while biological receptor activity is of higher dimension in chemistry space, and this is partly explainable by evolutionary pressures on ADME to deal with endobiotics and exobiotics."

Adjective
  1. 1
    living within the tissues of a host.
  2. 2
    Originating within an organ or biological system.

    "Even though PXR was initially identified as a xenobiotic receptor, emerging evidence has pointed to an equally important role of PXR as an endobiotic receptor that responds to a wide array of endogenous chemicals (endobiotics), such as bile acids and their intermediates, as well as certain steroid hormones."

Example

More examples

"Even though PXR was initially identified as a xenobiotic receptor, emerging evidence has pointed to an equally important role of PXR as an endobiotic receptor that responds to a wide array of endogenous chemicals (endobiotics), such as bile acids and their intermediates, as well as certain steroid hormones."

Etymology

From endo- + -biotic.

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Data sourced from Wiktionary, WordNet, CMU, and other open linguistic databases. Updated March 2026.