Estradiol

//ˌɛs.tɹəˈdaɪˌɔl// noun

noun ·Rare ·Advanced level

Definitions

Noun
  1. 1
    A natural estrogenic hormone that is a phenolic alcohol estra-1,3,5-triene-3,17-diol (C₁₈H₂₄O₂) secreted chiefly by the ovaries of all vertebrates, that is a major and the most potent of the naturally occurring estrogens; the semisynthetic esterified compound is used medicinally to treat estrogen deficiency and breast cancer. US, countable, uncountable

    "Gender-affirming hormone therapy may involve testosterone for trans people assigned female at birth (AFAB) and estradiol and anti-androgens for trans people AMAB."

  2. 2
    the most powerful female hormone that occurs naturally; synthesized and used to treat estrogen deficiency and breast cancer wordnet

Synonyms

All synonyms
dihydrotheelinoestradiol

Example

More examples

"Gender-affirming hormone therapy may involve testosterone for trans people assigned female at birth (AFAB) and estradiol and anti-androgens for trans people AMAB."

Etymology

Internationalism. From estratriene (“estra(triene)”) + diol. By surface analysis, estra- + di- + -ol.

Related phrases

estradiol benzoateestradiol undecylateestradiol valeratebreast cancer

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Data sourced from Wiktionary, WordNet, CMU, and other open linguistic databases. Updated March 2026.