Holoprosencephaly
noun
noun ·Rare ·Advanced level
Definitions
Noun
- 1 A congenital disorder involving insufficient division of the lobes of the brain during fetal development, resulting in skull and facial deformities ranging from minor cleft lip problems to cyclopia, in which a single eye develops where the nose would normally be. countable, uncountable
Synonyms
All synonymsEtymology
From Ancient Greek ὅλος (hólos, “whole”) + πρόσω (prósō, “forwards, onwards”) (referring to the prosencephalon (“forebrain”)) + ἐγκέφαλος (enképhalos, “brain”) + English -y (suffix denoting a condition), i.e. “condition of a whole (inappropriately divided) forebrain”. By surface analysis, holo- + pro- + -s- + encephal- + -y.
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Data sourced from Wiktionary, WordNet, CMU, and other open linguistic databases. Updated March 2026.