noun ·Uncommon ·Advanced level

Definitions

Noun

1. 1
   Down syndrome. countable, offensive, uncountable
2. 2
   a congenital disorder caused by having an extra 21st chromosome; results in a flat face and short stature and mental retardation wordnet

Synonyms

All synonyms

achromatic visionalbinismamentiaarrested developmentbackwardnessblithering idiocy

Etymology

From Mongol + -ism, coined by John Langdon Down.

Related phrases

down syndrome

Data sourced from Wiktionary, WordNet, CMU, and other open linguistic databases. Updated March 2026.