What does "mosaicism" mean?
The condition in which more than one genetically distinct population of cells coexist within one individual.
Mosaicism
noun
noun ·Rare ·Advanced level
Meaning at a glance
- Primary sense: The condition in which more than one genetically distinct population of cells coexist within one individual.
- Grammar: mosaicism is listed as noun.
- Nearest alternatives: cellular mosaicism, chromosome mosaicism, genetic mosaicism, karyotypic mosaicism.
- Useful contrasts: chromosomal homogeneity, chromosome stability, genetic homogeneity.
- Usage evidence: Some but not all of the cells that made up the fetus […] had an extra chromosome on the twentieth pair. A mosaicism, it was called.
How to use "mosaicism"
- Start with the primary definition, then check the part of speech before placing the word in a sentence.
- Compare nearby synonyms to make sure "mosaicism" carries the exact meaning, tone, and strength you need.
- Use the example sentence as a context check. If your sentence uses the word differently, confirm that the grammar still fits.
Meaning check
- Does the word fit the sentence's grammar?
- Does it match the intended tone rather than only the dictionary definition?
- Would a simpler synonym be clearer for the reader?
- Is there enough surrounding context to prevent ambiguity?
Source and review context
This entry combines structured lexical data with WordToolSet review checks. Definitions, examples, synonyms, and usage notes may come from different source tables, so the page is designed to show evidence from more than one angle before you rely on "mosaicism" in a final draft.
If a word has several senses, prefer the sense that matches your sentence's grammar and surrounding context. A correct definition can still be the wrong choice when the sentence needs a different register, emphasis, or level of specificity.
Before you rely on this definition
Read the first definition as a starting point, then check the example, synonyms, and part of speech before treating "mosaicism" as the right word for your sentence.
If your draft is formal, technical, persuasive, or sensitive, compare "mosaicism" with a nearby alternative so the final choice matches both meaning and reader expectation.
Compare nearby meanings
- Use synonyms when you need a softer, stronger, simpler, or more specific word.
- Use antonyms to check the boundary of the meaning and avoid accidental contrast.
- Use the example sentence to confirm the word behaves naturally in context.
- Keep the original wording when a replacement adds complexity without improving precision.
Definition decision workflow
1. Identify the role
Check whether "mosaicism" is acting as noun in your sentence. A definition is only useful when the grammar matches the way the word is being used.
2. Test the nearest option
Compare it with "cellular mosaicism" and other nearby choices to see whether the sentence needs a softer, stronger, or more familiar word.
3. Confirm with context
Use the example sentence below as an evidence check, then read your own sentence out loud to catch tone or rhythm problems.
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Final meaning check
Before publishing a sentence with "mosaicism", ask whether the word helps the reader understand the idea faster. A precise word should reduce confusion, not simply make the sentence look more polished.
When the definition, synonym evidence, and example context point in the same direction, the word is usually a safer choice. When they conflict, revise the sentence or choose a clearer alternative.
Definitions
Noun
- 1 The condition in which more than one genetically distinct population of cells coexist within one individual. countable, uncountable
"Some but not all of the cells that made up the fetus […] had an extra chromosome on the twentieth pair. A mosaicism, it was called."
- 2 the condition in which an organism has two or more cell populations that differ in genetic makeup wordnet
Synonyms
All synonyms cellular mosaicismchromosome mosaicismgenetic mosaicismkaryotypic mosaicismlocal mosaicismregional mosaicism
Antonyms
chromosomal homogeneitychromosome stabilitygenetic homogeneitygenetic stability
Example
"Some but not all of the cells that made up the fetus […] had an extra chromosome on the twentieth pair. A mosaicism, it was called."
Common questions
What is a synonym for "mosaicism"?
Common synonyms include: cellular mosaicism, chromosome mosaicism, genetic mosaicism, karyotypic mosaicism, local mosaicism, regional mosaicism.
How do you use "mosaicism" in a sentence?
Some but not all of the cells that made up the fetus […] had an extra chromosome on the twentieth pair. A mosaicism, it was called.
Etymology
From mosaic + -ism.