What does "proband" mean?

An individual who presents with a genetic disorder or other specific characteristic, when this leads to the genetic investigation of the individual's family.

What is a synonym for "proband"?

Common synonyms include: propositus.

Proband

noun

noun ·Rare ·Advanced level

Definitions

Noun

1
An individual who presents with a genetic disorder or other specific characteristic, when this leads to the genetic investigation of the individual's family.
"The proband was 8 years old and had a dyseidetic pattern, as did his father, who was also tested."

Synonyms

All synonyms

propositus

Example

More examples

"The proband was 8 years old and had a dyseidetic pattern, as did his father, who was also tested."

Etymology

From international scientific vocabulary, from New Latin, from Latin probandus (“the one to be tested”) (denoting, in this application, the first one tested); By surface analysis, probe + -and.

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Data sourced from Wiktionary, WordNet, CMU, and other open linguistic databases. Updated March 2026.