Simvastatin

//ˈsɪm.vəˌstæt.n̩// noun

Definitions

Noun
  1. 1
    A semisynthetic drug C₂₅H₃₈O₅ that decreases the level of cholesterol in the bloodstream and is derived from a compound produced by a mold (Aspergillus terreus). countable, uncountable

    "The last compound, gemfibrozil is the sole antilipidemic compound found (up to 3 ng/L) in a USA survey of 18 DWTPs whereas atorvastatin, simvastatin and their metabolites, the other studied compounds, were absent (Benotti et al., 2009). In our study, the two statins identified at the intake of the DWTP were eliminated by dioxychlorination (>99%) whereas bezafibrate, clofibric acid and gemfibrozil were only moderately removed with percentages of 37%, 68% and 11%, respectively although it has been reported that gemfibrozil and clofibric acid are readily oxidized with chlorine dioxide in spiked drinking water whereas bezafibrate remains unchanged (Huber et al., 2005a)."

  2. 2
    an oral lipid-lowering medicine (trade name Zocor) administered to reduce blood cholesterol levels; recommended after heart attacks wordnet

Etymology

Probably from sim- (“alteration of synthetic”) + -vastatin (“HMG CoA reductase inhibitor”).

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