What does "simvastatin" mean?
A semisynthetic drug C₂₅H₃₈O₅ that decreases the level of cholesterol in the bloodstream and is derived from a compound produced by a mold (Aspergillus terreus).
Simvastatin
/ˈsɪm.vəˌstæt.n̩/ noun
noun ·Rare ·Advanced level
Meaning at a glance
- Primary sense: A semisynthetic drug C₂₅H₃₈O₅ that decreases the level of cholesterol in the bloodstream and is derived from a compound produced by a mold (Aspergillus terreus).
- Grammar: simvastatin is listed as noun.
- Nearest alternatives: zocor.
- Usage evidence: The last compound, gemfibrozil is the sole antilipidemic compound found (up to 3 ng/L) in a USA survey of 18 DWTPs whereas atorvastatin, simvastatin and their metabolites, the other studied compounds, were absent (Benotti et al., 2009). In our study, the two statins identified at the intake of the DWTP were eliminated by dioxychlorination (>99%) whereas bezafibrate, clofibric acid and gemfibrozil were only moderately removed with percentages of 37%, 68% and 11%, respectively although it has been reported that gemfibrozil and clofibric acid are readily oxidized with chlorine dioxide in spiked drinking water whereas bezafibrate remains unchanged (Huber et al., 2005a).
How to use "simvastatin"
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- Compare nearby synonyms to make sure "simvastatin" carries the exact meaning, tone, and strength you need.
- Use the example sentence as a context check. If your sentence uses the word differently, confirm that the grammar still fits.
Meaning check
- Does the word fit the sentence's grammar?
- Does it match the intended tone rather than only the dictionary definition?
- Would a simpler synonym be clearer for the reader?
- Is there enough surrounding context to prevent ambiguity?
Source and review context
This entry combines structured lexical data with WordToolSet review checks. Definitions, examples, synonyms, and usage notes may come from different source tables, so the page is designed to show evidence from more than one angle before you rely on "simvastatin" in a final draft.
If a word has several senses, prefer the sense that matches your sentence's grammar and surrounding context. A correct definition can still be the wrong choice when the sentence needs a different register, emphasis, or level of specificity.
Before you rely on this definition
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Compare nearby meanings
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Definition decision workflow
1. Identify the role
Check whether "simvastatin" is acting as noun in your sentence. A definition is only useful when the grammar matches the way the word is being used.
2. Test the nearest option
Compare it with "zocor" and other nearby choices to see whether the sentence needs a softer, stronger, or more familiar word.
3. Confirm with context
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Final meaning check
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When the definition, synonym evidence, and example context point in the same direction, the word is usually a safer choice. When they conflict, revise the sentence or choose a clearer alternative.
Definitions
Noun
- 1 A semisynthetic drug C₂₅H₃₈O₅ that decreases the level of cholesterol in the bloodstream and is derived from a compound produced by a mold (Aspergillus terreus). countable, uncountable
"The last compound, gemfibrozil is the sole antilipidemic compound found (up to 3 ng/L) in a USA survey of 18 DWTPs whereas atorvastatin, simvastatin and their metabolites, the other studied compounds, were absent (Benotti et al., 2009). In our study, the two statins identified at the intake of the DWTP were eliminated by dioxychlorination (>99%) whereas bezafibrate, clofibric acid and gemfibrozil were only moderately removed with percentages of 37%, 68% and 11%, respectively although it has been reported that gemfibrozil and clofibric acid are readily oxidized with chlorine dioxide in spiked drinking water whereas bezafibrate remains unchanged (Huber et al., 2005a)."
- 2 an oral lipid-lowering medicine (trade name Zocor) administered to reduce blood cholesterol levels; recommended after heart attacks wordnet
Synonyms
All synonymsExample
"The last compound, gemfibrozil is the sole antilipidemic compound found (up to 3 ng/L) in a USA survey of 18 DWTPs whereas atorvastatin, simvastatin and their metabolites, the other studied compounds, were absent (Benotti et al., 2009). In our study, the two statins identified at the intake of the DWTP were eliminated by dioxychlorination (>99%) whereas bezafibrate, clofibric acid and gemfibrozil were only moderately removed with percentages of 37%, 68% and 11%, respectively although it has been reported that gemfibrozil and clofibric acid are readily oxidized with chlorine dioxide in spiked drinking water whereas bezafibrate remains unchanged (Huber et al., 2005a)."
Common questions
What is a synonym for "simvastatin"?
Common synonyms include: zocor.
How do you use "simvastatin" in a sentence?
The last compound, gemfibrozil is the sole antilipidemic compound found (up to 3 ng/L) in a USA survey of 18 DWTPs whereas atorvastatin, simvastatin and their metabolites, the other studied compounds, were absent (Benotti et al., 2009). In our study, the two statins identified at the intake of the DWTP were eliminated by dioxychlorination (>99%) whereas bezafibrate, clofibric acid and gemfibrozil were only moderately removed with percentages of 37%, 68% and 11%, respectively although it has been reported that gemfibrozil and clofibric acid are readily oxidized with chlorine dioxide in spiked drinking water whereas bezafibrate remains unchanged (Huber et al., 2005a).
How do you pronounce "simvastatin"?
Pronounced /ˈsɪm.vəˌstæt.n̩/.
Etymology
Probably from sim- (“alteration of synthetic”) + -vastatin (“HMG CoA reductase inhibitor”).