What does "substituent" mean?

Any atom, group, or radical substituted for another, or entering a molecule in place of some other part which is removed.

What is a synonym for "substituent"?

Common synonyms include: alternate, alternative, analogy, backup, change, changeling.

Pronounced /[sʌbˈstɪtʃuənt]/.

/[sʌbˈstɪtʃuənt]/ noun

noun ·Uncommon ·Advanced level

Noun

1
Any atom, group, or radical substituted for another, or entering a molecule in place of some other part which is removed.
"Other highly effective heterocyclic substituents were pyrazinyl and quinoxalyl."
2
Pro-form.

"Other highly effective heterocyclic substituents were pyrazinyl and quinoxalyl."

Data sourced from Wiktionary, WordNet, CMU, and other open linguistic databases. Updated March 2026.