Tolbutamide

noun

noun ·Rare ·Advanced level

Definitions

Noun
  1. 1
    A drug that blocks potassium channels, used in the treatment of diabetes. countable, uncountable

    "The cryophilic phenotype of the atu mutant was alleviated to some extent by administering rotenone, a pharmacological inhibitor of oxidative phosphorylation, but not tolbutamide, a sulphonylurea that stimulates metabolic rate by raising the lymphatic concentration of glucose."

  2. 2
    sulfonylurea; an oral antidiabetic drug (trade name Orinase) used in the treatment of adult-onset diabetes mellitus wordnet

Synonyms

All synonyms
orinase

Example

More examples

"The cryophilic phenotype of the atu mutant was alleviated to some extent by administering rotenone, a pharmacological inhibitor of oxidative phosphorylation, but not tolbutamide, a sulphonylurea that stimulates metabolic rate by raising the lymphatic concentration of glucose."

Related phrases

potassium channel

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Data sourced from Wiktionary, WordNet, CMU, and other open linguistic databases. Updated March 2026.