Mortification

It is a great mortification to the vanity of man, that his utmost art and industry can never equal the meanest of nature's productions, either for beauty or value.

Anne's mortification was as evident as Gilbert's satisfaction.

Near-synonym: humiliation

Certainly a little mortification appears very becoming in a wife—don't you think it will do her good to let her Pine a little.

He felt stunned—mortification, sorrow, and anger, mingled together: the past was like a dream, and the future swam indistinctly before him.

The humor of my proposition appealed more strongly to Miss Trevor than I had looked for, and from that time forward she became her old self again; for, even after she had conquered her love for the Celebrity, the mortification of having been jilted by him remained.

And then there's the fever and the mortification—if it took bad ways he'd quickly be gone.