Protease

As a matter of fact the casein protease digests boiled and coagulated serum far more easily than unboiled serum, as set forth by the following experiments.

All were tested for their ability to clot milk and to hydrolyze denatured hemoglobin, egg albumin, protamine (salmon), histone (calf thymus), and benzoyl-l-arginineamide. In no case was any trace of protease activity detected.

For our purposes, it is sufficient to note that dysregulation of desquamatory protease activity in the SC is often involved in conditions of compromised skin barrier.